Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane

Zamprogno et al. report a lung-on-a-chip of the second generation that mimics an array of alveoli with in vivo-like dimensions, based on a thin, stretchable collagen-elastin membrane used to reproduce the air-blood barrier functions. The membrane is stable, can be cultured on both sides for weeks, i...

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Bibliographic Details
Main Authors: Pauline Zamprogno, Simon Wüthrich, Sven Achenbach, Giuditta Thoma, Janick D. Stucki, Nina Hobi, Nicole Schneider-Daum, Claus-Michael Lehr, Hanno Huwer, Thomas Geiser, Ralph A. Schmid, Olivier T. Guenat
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01695-0