Raster plots machine learning to predict the seizure liability of drugs and to identify drugs

Abstract In vitro microelectrode array (MEA) assessment using human induced pluripotent stem cell (iPSC)-derived neurons holds promise as a method of seizure and toxicity evaluation. However, there are still issues surrounding the analysis methods used to predict seizure and toxicity liability as we...

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Bibliographic Details
Main Authors: N. Matsuda, A. Odawara, K. Kinoshita, A. Okamura, T. Shirakawa, I. Suzuki
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-05697-8