Raster plots machine learning to predict the seizure liability of drugs and to identify drugs
Abstract In vitro microelectrode array (MEA) assessment using human induced pluripotent stem cell (iPSC)-derived neurons holds promise as a method of seizure and toxicity evaluation. However, there are still issues surrounding the analysis methods used to predict seizure and toxicity liability as we...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-02-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-05697-8 |