Bioclickable Mussel-Derived Peptides With Immunoregulation for Osseointegration of PEEK

Bioclickable Mussel-Derived Peptides With Immunoregulation for Osseointegration of PEEK

Polyether ether ketone (PEEK)–based biomaterials have been widely used in the field of spine and joint surgery. However, lack of biological activity limits their further clinical application. In this study, we synthesized a bioclickable mussel-derived peptide Azide-DOPA4 as a PEEK surface coating mo...

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Bibliographic Details
Main Authors: Huan Zhao, Xiaokang Wang, Wen Zhang, Lin Wang, Can Zhu, Yingkang Huang, Rongrong Chen, Xu Chen, Miao Wang, Guoqing Pan, Qin Shi, Xichao Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
PEEK
clickable mussel-biomimetic peptide
bone morphogenetic protein 2 functional peptides
bio-orthogonal reaction
osseointegration
FOXP3+ regulatory T cells
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.780609/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2021.780609/full

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