Exosomal microRNAs in the DLK1-DIO3 imprinted region derived from cancer-associated fibroblasts promote progression of hepatocellular carcinoma by targeting hedgehog interacting protein

Exosomal microRNAs in the DLK1-DIO3 imprinted region derived from cancer-associated fibroblasts promote progression of hepatocellular carcinoma by targeting hedgehog interacting protein

Abstract Background Hepatocellular carcinoma (HCC) is the sixth most commonly diagnosed cancer and third leading cause of cancer-related death worldwide in 2020. Exosomes derived from cancer-associated fibroblasts (CAFs-exo) can promote tumor progression in various human cancers. However, the underl...

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Bibliographic Details
Main Authors: An-Li Jin, Lin Ding, Wen-Jing Yang, Te Liu, Wei Chen, Tong Li, Chun-Yan Zhang, Bai-Shen Pan, Shuang-Jian Qiu, Jian Zhou, Jia Fan, Wei Guo, Xin-Rong Yang, Bei-Li Wang
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Gastroenterology
Subjects:
Hepatocellular carcinoma
Cancer-associated fibroblasts
Exosomes
DLK1-DIO3 microRNA cluster
Hedgehog interacting protein
Online Access:https://doi.org/10.1186/s12876-022-02594-2

Internet

https://doi.org/10.1186/s12876-022-02594-2

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