MicroRNA-218 instructs proper assembly of hippocampal networks

MicroRNA-218 instructs proper assembly of hippocampal networks

The assembly of the mammalian brain is orchestrated by temporally coordinated waves of gene expression. Post-transcriptional regulation by microRNAs (miRNAs) is a key aspect of this program. Indeed, deletion of neuron-enriched miRNAs induces strong developmental phenotypes, and miRNA levels are alte...

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Bibliographic Details
Main Authors: Seth R Taylor, Mariko Kobayashi, Antonietta Vilella, Durgesh Tiwari, Norjin Zolboot, Jessica X Du, Kathryn R Spencer, Andrea Hartzell, Carol Girgiss, Yusuf T Abaci, Yufeng Shao, Claudia De Sanctis, Gian Carlo Bellenchi, Robert B Darnell, Christina Gross, Michele Zoli, Darwin K Berg, Giordano Lippi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-10-01
Series:eLife
Subjects:
microRNA
development
network stability
GABAergic interneurons
miR-218
Online Access:https://elifesciences.org/articles/82729

Internet

https://elifesciences.org/articles/82729

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