Na,K-ATPase Acts as a Beta-Amyloid Receptor Triggering Src Kinase Activation

Beta-amyloid (Aβ) has a dual role, both as an important factor in the pathology of Alzheimer’s disease and as a regulator in brain physiology. The inhibitory effect of Aβ<sub>42</sub> oligomers on Na,K-ATPase contributes to neuronal dysfunction in Alzheimer’s disease. Still, the physiolo...

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Main Authors: Irina Yu. Petrushanko, Artem M. Tverskoi, Evgeny P. Barykin, Aleksandra V. Petrovskaya, Maria A. Strelkova, Olga G. Leonova, Anastasia A. Anashkina, Anna P. Tolstova, Alexei A. Adzhubei, Anna Yu. Bogdanova, Alexander A. Makarov, Vladimir A. Mitkevich
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/17/2753