Cyclotides Suppress Human T-Lymphocyte Proliferation by an Interleukin 2-Dependent Mechanism.

Cyclotides Suppress Human T-Lymphocyte Proliferation by an Interleukin 2-Dependent Mechanism.

Cyclotides are a diverse and abundant group of ribosomally synthesized plant peptides containing a unique cyclic cystine-knotted topology that confers them with remarkable stability. Kalata B1, a representative member of this family of mini-proteins, has been found to inhibit the proliferation of hu...

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Bibliographic Details
Main Authors: Carsten Gründemann, Kathrin Thell, Karin Lengen, Manuel Garcia-Käufer, Yen-Hua Huang, Roman Huber, David J Craik, Gernot Schabbauer, Christian W Gruber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3694003?pdf=render

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http://europepmc.org/articles/PMC3694003?pdf=render

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