Endothelial Cell-derived Extracellular Vesicles Size-dependently Exert Procoagulant Activity Detected by Thromboelastometry

Abstract Endothelial cells (ECs) are major modulators of hemostasis by expressing and releasing pro- and anticoagulant mediators into the circulation. Previous studies showed that cultured ECs release procoagulant mediators into cell culture supernatants as evidenced by the reduction of viscoelastic...

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Bibliographic Details
Main Authors: Wolfgang Holnthoner, Cornelia Bonstingl, Carina Hromada, Severin Muehleder, Johannes Zipperle, Stefan Stojkovic, Heinz Redl, Johann Wojta, Herbert Schöchl, Johannes Grillari, Sylvia Weilner, Christoph J. Schlimp
Format: Article
Language:English
Published: Nature Portfolio 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03159-0