Purification of Monoclonal Antibodies Using a Fiber Based Cation-Exchange Stationary Phase: Parameter Determination and Modeling

Purification of Monoclonal Antibodies Using a Fiber Based Cation-Exchange Stationary Phase: Parameter Determination and Modeling

Monoclonal antibodies (mAb) currently dominate the market for protein therapeutics. Because chromatography unit operations are critical for the purification of therapeutic proteins, the process integration of novel chromatographic stationary phases, driven by the demand for more economic process sch...

Full description

Bibliographic Details
Main Authors: Jan Schwellenbach, Steffen Zobel, Florian Taft, Louis Villain, Jochen Strube
Format: Article
Language:English
Published: MDPI AG 2016-10-01
Series:Bioengineering
Subjects:
monoclonal antibodies
downstream processing
cation-exchange chromatography
model
simulation
parameter determination
Online Access:http://www.mdpi.com/2306-5354/3/4/24

Internet

http://www.mdpi.com/2306-5354/3/4/24

Similar Items