A Multitarget Approach against Neuroinflammation: Alkyl Substituted Coumarins as Inhibitors of Enzymes Involved in Neurodegeneration

A Multitarget Approach against Neuroinflammation: Alkyl Substituted Coumarins as Inhibitors of Enzymes Involved in Neurodegeneration

Neurodegenerative disorders (NDs) include a large range of diseases characterized by neural dysfunction with a multifactorial etiology. The most common NDs are Alzheimer’s disease and Parkinson’s disease, in which cholinergic and dopaminergic systems are impaired, respectively. Despite different bra...

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Bibliographic Details
Main Authors: Emanuela Berrino, Simone Carradori, Fabrizio Carta, Francesco Melfi, Marialucia Gallorini, Giulio Poli, Tiziano Tuccinardi, José G. Fernández-Bolaños, Óscar López, Jacobus P. Petzer, Anél Petzer, Paolo Guglielmi, Daniela Secci, Claudiu T. Supuran
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Antioxidants
Subjects:
carbonic anhydrase
inhibitors
monoamine oxidase (MAO)
coumarin
cholinesterase
Parkinson’s disease
Online Access:https://www.mdpi.com/2076-3921/12/12/2044

Internet

https://www.mdpi.com/2076-3921/12/12/2044

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