Improved method for efficient imaging of intracellular Cl- with Cl-Sensor using conventional fluorescence setup

Improved method for efficient imaging of intracellular Cl- with Cl-Sensor using conventional fluorescence setup

Chloride (Cl-) homeostasis is known to be fundamental for central nervous system functioning. Alterations in intracellular Cl- concentration ([Cl-]i) and changes in the efficacy of Cl- extrusion are involved in numerous neurological disorders. Therefore there is a strong need for studies of the dyna...

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Bibliographic Details
Main Authors: Perrine eFriedel, Piotr eBregestovski, Igor eMedina
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-04-01
Series:Frontiers in Molecular Neuroscience
Subjects:
KCC2
Neuron
Cl-sensor
fluorescent bioSensors
intracellular chloride
non-invasive monitoring
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2013.00007/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2013.00007/full

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