A statistical model for describing and simulating microbial community profiles.

Many methods have been developed for statistical analysis of microbial community profiles, but due to the complex nature of typical microbiome measurements (e.g. sparsity, zero-inflation, non-independence, and compositionality) and of the associated underlying biology, it is difficult to compare or...

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Bibliographic Details
Main Authors: Siyuan Ma, Boyu Ren, Himel Mallick, Yo Sup Moon, Emma Schwager, Sagun Maharjan, Timothy L Tickle, Yiren Lu, Rachel N Carmody, Eric A Franzosa, Lucas Janson, Curtis Huttenhower
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-09-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1008913