The Desmosomal Cadherin Desmoglein-2 Experiences Mechanical Tension as Demonstrated by a FRET-Based Tension Biosensor Expressed in Living Cells

The Desmosomal Cadherin Desmoglein-2 Experiences Mechanical Tension as Demonstrated by a FRET-Based Tension Biosensor Expressed in Living Cells

Cell-cell junctions are critical structures in a number of tissues for mechanically coupling cells together, cell-to-cell signaling, and establishing a barrier. In many tissues, desmosomes are an important component of cell-cell junctions. Loss or impairment of desmosomes presents with clinical phen...

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Bibliographic Details
Main Authors: Sindora R. Baddam, Paul T. Arsenovic, Vani Narayanan, Nicole R. Duggan, Carl R. Mayer, Shaston T. Newman, Dahlia A. Abutaleb, Abhinav Mohan, Andrew P. Kowalczyk, Daniel E. Conway
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Cells
Subjects:
desmosomes
mechanobiology
cell biophysics
Online Access:http://www.mdpi.com/2073-4409/7/7/66

Internet

http://www.mdpi.com/2073-4409/7/7/66

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