Auranofin and ICG-001 Emerge Synergistic Anti-tumor Effect on Canine Breast Cancer by Inducing Apoptosis via Mitochondrial Pathway

Auranofin and ICG-001 Emerge Synergistic Anti-tumor Effect on Canine Breast Cancer by Inducing Apoptosis via Mitochondrial Pathway

Canine breast cancer (CBC) is the most common spontaneous tumor in intact female dogs, especially in developing countries. The effective anti-tumor agents or therapies for the clinical treatment of CBC are still in need. Auranofin (AF) is a gold complex that has been attested by FDA for treating hum...

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Bibliographic Details
Main Authors: Zhaoyan Lin, Zixiang Lin, Ying Zhao, Nan Cheng, Di Zhang, Jiahao Lin, Hong Zhang, Degui Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Veterinary Science
Subjects:
auranofin
ICG-001
mitochondrial pathway
ROS
CBC
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2021.772687/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2021.772687/full

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