Human Chondrocyte Activation by Toxins From Premolis semirufa, an Amazon Rainforest Moth Caterpillar: Identifying an Osteoarthritis Signature

Human Chondrocyte Activation by Toxins From Premolis semirufa, an Amazon Rainforest Moth Caterpillar: Identifying an Osteoarthritis Signature

Pararamosis is a disease that occurs due to contact with the hairs of the larval stage of the Brazilian moth Premolis semirufa. Envenomation induces osteoarticular alterations with cartilage impairment that resembles joint synovitis. Thus, the toxic venom present in the caterpillar hairs interferes...

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Bibliographic Details
Main Authors: Isadora M. Villas-Boas, Giselle Pidde, Flavio Lichtenstein, Ana Tung Ching Ching, Inácio de Loiola Meirelles Junqueira-de-Azevedo, Carlos DeOcesano-Pereira, Carlos Eduardo Madureira Trufen, Ana Marisa Chudzinski-Tavassi, Kátia Luciano Pereira Morais, Denise V. Tambourgi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
osteoarthritis
toxins
caterpillar
chondrocyte
mediators
cell signaling
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.02191/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.02191/full

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