Bacterial infection reinforces host metabolic flux from arginine to spermine for NLRP3 inflammasome evasion

Bacterial infection reinforces host metabolic flux from arginine to spermine for NLRP3 inflammasome evasion

Summary: Hosts recognize cytosolic microbial infection via the nucleotide-binding domain-like receptor (NLR) protein family, triggering inflammasome complex assembly to provoke pyroptosis or cytokine-related caspase-1-dependent antimicrobial responses. Pathogens have evolved diverse strategies to an...

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Bibliographic Details
Main Authors: Jiatiao Jiang, Wenwen Wang, Fei Sun, Yuanxing Zhang, Qin Liu, Dahai Yang
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Cell Reports
Subjects:
Edwardsiella piscicida
arginine metabolism
spermine
K+ efflux
NLRP3 inflammasome
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721001467

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http://www.sciencedirect.com/science/article/pii/S2211124721001467

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