A Fluorescent Probe to Measure DNA Damage and Repair.

DNA damage and repair is a fundamental process that plays an important role in cancer treatment. Base excision repair (BER) is a major repair pathway that often leads to drug resistance in DNA-targeted cancer chemotherapy. In order to measure BER, we have developed a near infrared (NIR) fluorescent...

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Bibliographic Details
Main Authors: Allison G Condie, Yan Yan, Stanton L Gerson, Yanming Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4550365?pdf=render