A unique cytotoxic CD4+ T cell‐signature defines critical COVID‐19

A unique cytotoxic CD4+ T cell‐signature defines critical COVID‐19

Abstract Objectives SARS‐CoV‐2 infection causes a spectrum of clinical disease presentation, ranging from asymptomatic to fatal. While neutralising antibody (NAb) responses correlate with protection against symptomatic and severe infection, the contribution of the T‐cell response to disease resoluti...

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Bibliographic Details
Main Authors: Sarah Baird, Caroline L Ashley, Felix Marsh‐Wakefield, Sibel Alca, Thomas M Ashhurst, Angela L Ferguson, Hannah Lukeman, Claudio Counoupas, Jeffrey J Post, Pamela Konecny, Adam Bartlett, Marianne Martinello, Rowena A Bull, Andrew Lloyd, Alice Grey, Owen Hutchings, Umaimainthan Palendira, Warwick J Britton, Megan Steain, James A Triccas
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Clinical & Translational Immunology
Subjects:
CD4‐CTLs
COVID‐19
SARS‐CoV‐2
spectral cytometry
T cells
Online Access:https://doi.org/10.1002/cti2.1463

Internet

https://doi.org/10.1002/cti2.1463

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