CD19 CAR-NK CONSTRUCTION WITH A NEW HINGE AND GITRL CO-EXPRESSION FOR TREG ACTIVITY INHIBITION
Introduction: Chimeric Antigen Receptor T (CAR-T) cell therapy has emerged as a promising approach in which autologous T cells are engineered to recognize a specific target. Although the clinical responses are encouraging, nearly 60% of large B cell lymphoma patients have disease progression after a...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-10-01
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Series: | Hematology, Transfusion and Cell Therapy |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2531137923011835 |