Targeting Focal Adhesion Kinase Suppresses the Malignant Phenotype in Rhabdomyosarcoma Cells

Targeting Focal Adhesion Kinase Suppresses the Malignant Phenotype in Rhabdomyosarcoma Cells

Despite the tremendous advances in the treatment of childhood solid tumors, rhabdomyosarcoma (RMS) continues to provide a therapeutic challenge. Children with metastatic or relapsed disease have a disease-free survival rate under 30%. Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase that...

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Bibliographic Details
Main Authors: Alicia M. Waters, Laura L. Stafman, Evan F. Garner, Smitha Mruthyunjayappa, Jerry E. Stewart, Elizabeth Mroczek-Musulman, Elizabeth A. Beierle
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523316300481

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http://www.sciencedirect.com/science/article/pii/S1936523316300481

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