A flexible, modular and versatile functional part assembly toolkit for gene cluster engineering in Streptomyces

Streptomyces has enormous potential to produce novel natural products (NPs) as it harbors a huge reservoir of uncharacterized and silent natural product biosynthetic gene clusters (BGCs). However, the lack of efficient gene cluster engineering strategies has hampered the pace of new drug discovery....

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Bibliographic Details
Main Authors: Xuejin Zhao, Yeqing Zong, Qiuli Lou, Chenrui Qin, Chunbo Lou
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-03-01
Series:Synthetic and Systems Biotechnology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X23001102