Medullary astrocytes mediate irregular breathing patterns generation in chronic heart failure through purinergic P2X7 receptor signalling

Medullary astrocytes mediate irregular breathing patterns generation in chronic heart failure through purinergic P2X7 receptor signalling

Summary: Background: Breathing disorders (BD) (apnoeas/hypopneas, periodic breathing) are highly prevalent in chronic heart failure (CHF) and are associated with altered central respiratory control. Ample evidence identifies the retrotrapezoid nucleus (RTN) as an important chemosensitivity region f...

Full description

Bibliographic Details
Main Authors: Camilo Toledo, Esteban Díaz-Jara, Hugo S. Diaz, Karla G. Schwarz, Katherin V. Pereyra, Alexandra Las Heras, Angélica Rios-Gallardo, David C. Andrade, Thiago Moreira, Ana Takakura, Noah J. Marcus, Rodrigo Del Rio
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:EBioMedicine
Subjects:
Chronic heart failure
Disordered breathing
Astrocyte
Retrotrapezoid nucleus
P2X7 receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422002250

Internet

http://www.sciencedirect.com/science/article/pii/S2352396422002250

Similar Items