A new strategy to generate functional insulin-producing cell lines by somatic gene transfer into pancreatic progenitors.

A new strategy to generate functional insulin-producing cell lines by somatic gene transfer into pancreatic progenitors.

BACKGROUND: There is increasing interest in developing human cell lines to be used to better understand cell biology, but also for drug screening, toxicology analysis and future cell therapy. In the endocrine pancreatic field, functional human beta cell lines are extremely scarce. On the other hand,...

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Bibliographic Details
Main Authors: Philippe Ravassard, Emilie Bricout-Neveu, Yasmine Hazhouz, Severine Pechberty, Jacques Mallet, Paul Czernichow, Raphael Scharfmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2649535?pdf=render

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http://europepmc.org/articles/PMC2649535?pdf=render

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