Interaction of HuDA and PABP at 5'UTR of mouse insulin2 regulates insulin biosynthesis.

Understanding the regulation of insulin biosynthesis is important as it plays a central role in glucose metabolism. The mouse insulin gene2 (Ins2) has two splice variants; long (Ins2L) and short (Ins2S), that differ only in their 5'UTR sequence and Ins2S is the major transcript which translate...

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Bibliographic Details
Main Authors: Poonam R Pandey, Rucha D Sarwade, Abdul Khalique, Vasudevan Seshadri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5874046?pdf=render