Development of Long-Acting Human Adrenomedullin Fc-Fusion Proteins

(1) Background: Human adrenomedullin (hAM) is a hypotensive peptide hormone that exerts powerful anti-inflammatory effects. AM also had therapeutic effects in various animal experimental models of disease. However, treatment required continuous administration as the half-life of native AM is short i...

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Bibliographic Details
Main Authors: Sayaka Nagata, Motoo Yamasaki, Nobuko Kuroishi, Kazuo Kitamura
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/11/7/1074