Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1
A defining feature of mitochondria is their maternal mode of inheritance. However, little is understood about the cellular mechanism through which paternal mitochondria, delivered from sperm, are eliminated from early mammalian embryos. Autophagy has been implicated in nematodes, but whether this me...
Autors principals: | Rebecca Rojansky, Moon-Yong Cha, David C Chan |
---|---|
Format: | Article |
Idioma: | English |
Publicat: |
eLife Sciences Publications Ltd
2016-11-01
|
Col·lecció: | eLife |
Matèries: | |
Accés en línia: | https://elifesciences.org/articles/17896 |
Ítems similars
-
Parkin regulation and neurodegenerative disorders
per: Chengwu eZhang, et al.
Publicat: (2016-01-01) -
Autophagy and autophagic cell death in sepsis: friend or foe?
per: Toshiaki Iba, et al.
Publicat: (2024-10-01) -
Metabolic, autophagic, and mitophagic activities in cancer initiation and progression
per: Anita Hjelmeland, et al.
Publicat: (2016-04-01) -
Maintaining the balance of TDP-43, mitochondria, and autophagy: a promising therapeutic strategy for neurodegenerative diseases
per: Chunhui Huang, et al.
Publicat: (2020-10-01) -
A secretory form of Parkin‐independent mitophagy contributes to the repertoire of extracellular vesicles released into the tumour interstitial fluid in vivo
per: Marissa Howard, et al.
Publicat: (2022-07-01)