Selection of Aspergillus fumigatus isolates carrying the G448S substitution in CYP51A gene after long-term treatment with voriconazole in an immunocompromised patient

We present a case of a 55-year-old man with a heart transplant who acquired Invasive Aspergillosis by Aspergillus fumigatus with the focus in the kidney. During about two years of antifungal treatment, most of the time with voriconazole, it was possible to obtain nine isolates of A. fumigatus, with...

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Bibliographic Details
Main Authors: Laís Pontes, Caio Augusto Gualtieri Beraquet, Teppei Arai, Akira Watanabe, Maria Luiza Moretti, Angelica Zaninelli Schreiber
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Medical Mycology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211753922000094