Widespread false gene gains caused by duplication errors in genome assemblies

Widespread false gene gains caused by duplication errors in genome assemblies

Abstract Background False duplications in genome assemblies lead to false biological conclusions. We quantified false duplications in popularly used previous genome assemblies for platypus, zebra finch, and Anna’s Hummingbird, and their new counterparts of the same species generated by the Vertebrat...

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Bibliographic Details
Main Authors: Byung June Ko, Chul Lee, Juwan Kim, Arang Rhie, Dong Ahn Yoo, Kerstin Howe, Jonathan Wood, Seoae Cho, Samara Brown, Giulio Formenti, Erich D. Jarvis, Heebal Kim
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Genome Biology
Subjects:
False duplication
Assembly error
Phasing error
De novo assembly
Vertebrate genome project
Online Access:https://doi.org/10.1186/s13059-022-02764-1

Internet

https://doi.org/10.1186/s13059-022-02764-1

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