Age-Related Increase of Collagen/Fibrin Deposition and High PAI-1 Production in Human Nasal Polyps

Age-Related Increase of Collagen/Fibrin Deposition and High PAI-1 Production in Human Nasal Polyps

Objective: Our previous studies showed an age-related increased prevalence of nasal polyps (NP) and reduced production of S100A8/9 in elderly patients with chronic rhinosinusitis with NP (CRSwNP). In this study, we investigated an unbiased age-related gene expression profile in CRSwNP subjects and h...

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Bibliographic Details
Main Authors: Ara Jo, Tae Gyu Choi, Jung Yeon Han, Mark H. Tabor, Narasaiah Kolliputi, Richard F. Lockey, Seong H. Cho
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Pharmacology
Subjects:
nasal polyps
aging
tissue remodeling
submucosal glands
antimicrobial peptides and proteins
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.845324/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.845324/full

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