M1 muscarinic receptor activation mediates cell death in M1-HEK293 cells.

M1 muscarinic receptor activation mediates cell death in M1-HEK293 cells.

HEK293 cells have been used extensively to generate stable cell lines to study G protein-coupled receptors, such as muscarinic acetylcholine receptors (mAChRs). The activation of M1 mAChRs in various cell types in vitro has been shown to be protective. To further investigate M1 mAChR-mediated cell s...

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Bibliographic Details
Main Authors: E Scott Graham, Kerhan K Woo, Miranda Aalderink, Sandie Fry, Jeffrey M Greenwood, Michelle Glass, Mike Dragunow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3759376?pdf=render

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http://europepmc.org/articles/PMC3759376?pdf=render

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