Research Progress of Endoplasmic Reticulum Stress PERK-eIF2α-AFT4-CHOP Signaling Pathway in Hematological Malignancies

The biosynthesis and maturation of proteins are primarily regulated by the endoplasmic reticulum in its physiological state. Thus, the disruption of physiological homeostasis initiates the buildup of unfolded and misfolded proteins in the endoplasmic reticulum, resulting in endoplasmic reticulum str...

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Bibliographic Details
Main Authors: HE Mengke, XU Zizhen, LI Junmin
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2024-02-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
Online Access:http://www.zlfzyj.com/en/article/doi/10.3971/j.issn.1000-8578.2024.23.0609