Purification of Functional HEV-ORF2 Protein from Inclusion Bodies for Vaccine and Diagnostic Applications

Purification of Functional HEV-ORF2 Protein from Inclusion Bodies for Vaccine and Diagnostic Applications

Introduction: Hepatitis E virus (HEV) causes emerging diseases in poor regions of the world. The ORF2 is the only protein encoded by the virus to make the viral capsid. The aggregation of proteins into inclusion bodies (IBs) while expressing ORF2 is a major challenge in bioengineering. Methods: The...

Full description

Bibliographic Details
Main Authors: Fatemeh Motevalli, Mohammad Reza Amiran, Mazyar Etemadzadeh, Golnaz Bahramali, Soroush Sardari, Seyede Zahra Moravej, Pooneh Rahimi, Abolfazl Fateh, Seyed Alireza Seyed Siamdoust, Mohammad Ali Zaheri Birgani, Mojtaba Hamidi-Fard
Format: Article
Language:English
Published: Pasteur Institute of Iran 2020-06-01
Series:Vaccine Research
Subjects:
hepatitis e virus
orf2
inclusion bodies
protein solubilization
Online Access:http://vacres.pasteur.ac.ir/article-1-207-en.html

Internet

http://vacres.pasteur.ac.ir/article-1-207-en.html

Similar Items