Zhen-Wu-Tang Induced Mitophagy to Protect Mitochondrial Function in Chronic Glomerulonephritis via PI3K/AKT/mTOR and AMPK Pathways

Zhen-Wu-Tang Induced Mitophagy to Protect Mitochondrial Function in Chronic Glomerulonephritis via PI3K/AKT/mTOR and AMPK Pathways

Chronic glomerulonephritis (CGN) is one of the major causes of end-stage kidney disease. Zhen-wu-tang (ZWT), as a famous Chinese herbal prescription, is widely used in China for CGN therapy in clinic. However, the mechanism of ZWT in CGN has not been fully understood. The present study explored the...

Full description

Bibliographic Details
Main Authors: Bihao Liu, Yiwen Cao, Dejuan Wang, Yuan Zhou, Peichun Zhang, Junbiao Wu, Junqi Chen, Jianguang Qiu, Jiuyao Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Pharmacology
Subjects:
chronic glomerulonephritis
Zhen-wu-tang
mitochondrial function
mitophagy
PI3K/Akt/mTOR pathway
AMPK pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.777670/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.777670/full

Similar Items