Dissecting the role of cancer‐associated fibroblast‐derived biglycan as a potential therapeutic target in immunotherapy resistance: A tumor bulk and single‐cell transcriptomic study

Dissecting the role of cancer‐associated fibroblast‐derived biglycan as a potential therapeutic target in immunotherapy resistance: A tumor bulk and single‐cell transcriptomic study

Abstract Introduction Cancer‐associated fibroblasts (CAFs) are correlated with the immunotherapy response. However, the culprits that link CAFs to immunotherapy resistance are still rarely investigated in real‐world studies. Objectives This study aims to systematically assess the landscape of fibrob...

Full description

Bibliographic Details
Main Authors: Shaoquan Zheng, Jie‐Ying Liang, Yuhui Tang, Jindong Xie, Yutian Zou, Anli Yang, Nan Shao, Xiaying Kuang, Fei Ji, Xuefeng Liu, Wenwen Tian, Weikai Xiao, Ying Lin
Format: Article
Language:English
Published: Wiley 2023-02-01
Series:Clinical and Translational Medicine
Subjects:
cancer‐associated fibroblasts
immunotherapy
tumor biomarker
tumor microenvironment
Online Access:https://doi.org/10.1002/ctm2.1189

Internet

https://doi.org/10.1002/ctm2.1189

Similar Items