Keratocyte Differentiation Is Regulated by NF-κB and TGFβ Signaling Crosstalk

Interleukin-1 (IL-1) and transforming growth factor-beta (TGFβ) are important cytokines involved in corneal wound healing. Here, we studied the effect of these cytokines on corneal stromal cell (keratocyte) differentiation. IL-1β treatment resulted in reduced keratocyte phenotype, as evident by morp...

Full description

Bibliographic Details
Main Authors: Xin Zhou, Junhong Li, Ludvig J. Backman, Patrik Danielson
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/19/11073