A Novel Exosome-Relevant Molecular Classification Uncovers Distinct Immune Escape Mechanisms and Genomic Alterations in Gastric Cancer

A Novel Exosome-Relevant Molecular Classification Uncovers Distinct Immune Escape Mechanisms and Genomic Alterations in Gastric Cancer

Objective: Gastric cancer (GC) is a highly heterogeneous malignant carcinoma. This study aimed to conduct an exosome-based classification for assisting personalized therapy for GC.Methods: Based on the expression profiling of prognostic exosome-related genes, GC patients in The Cancer Genome Atlas (...

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Bibliographic Details
Main Authors: Yubiao Lin, Kaida Huang, Zhezhen Cai, Yide Chen, Lihua Feng, Yingqin Gao, Wenhui Zheng, Xin Fan, Guoqin Qiu, Jianmin Zhuang, Shuitu Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
gastric cancer
exosomes
immunotherapy
tumor microenvironment
immune escape
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.884090/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.884090/full

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