Interferon Gamma-Inducible Protein 16 of Peripheral Blood Mononuclear Cells May Sense Hepatitis B Virus Infection and Regulate the Antiviral Immunity

Interferon Gamma-Inducible Protein 16 of Peripheral Blood Mononuclear Cells May Sense Hepatitis B Virus Infection and Regulate the Antiviral Immunity

Interferon gamma-inducible protein 16 (IFI16) is a DNA sensor protein, which triggers interferon-beta (IFN-β) production. However, the role of IFI16 in the innate immunity against hepatitis B virus (HBV) remains controversial. Peripheral blood mononuclear cells (PBMCs) and serum specimens were colle...

Full description

Bibliographic Details
Main Authors: Yu-Qing Lu, Jing Wu, Xiang-Ji Wu, Hui Ma, Yan-Xiu Ma, Rong Zhang, Meng-Nan Su, Nan Wu, Gong-Yin Chen, Hong-Song Chen, Xiao-Ben Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
IFI16
HBV
PBMCs
innate immunity
interferon
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.790036/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2021.790036/full

Similar Items