The Promotion of Genomic Instability in Human Fibroblasts by Adenovirus 12 Early Region 1B 55K Protein in the Absence of Viral Infection

The adenovirus 12 early region 1B55K (Ad12E1B55K) protein has long been known to cause non-random damage to chromosomes 1 and 17 in human cells. These sites, referred to as Ad12 modification sites, have marked similarities to classic fragile sites. In the present report we have investigated the effe...

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Bibliographic Details
Main Authors: Tareq Abualfaraj, Nafiseh Chalabi Hagkarim, Robert Hollingworth, Laura Grange, Satpal Jhujh, Grant S. Stewart, Roger J. Grand
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/13/12/2444