lncRNA HAND2-AS1 is downregulated in osteoarthritis and regulates IL-6 expression in chondrocytes

Abstract Background Osteoarthritis (OA) is a leading cause of disability. The incidence of OA is progressively rising due to the diminishing levels of physical activity and ever-expanding aging population. However, the mainstay for OA treatment only can improve symptoms without delay the progression...

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Bibliographic Details
Main Authors: Zhenxing Si, Shifeng Zhou, Zilong Shen, Feiyu Luan, Jinglong Yan
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-021-02216-9