Evolution of the fish heart by sub/neofunctionalization of an elastin gene

The bulbus arteriosus is an organ unique to the heart of teleosts, composed of specialized smooth muscle. Here, the authors show that the gene elastin b, which regulates cell fate of cardiac precursor cells into smooth muscle, evolved after whole-genome duplication and neofunctionalization in teleos...

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Bibliographic Details
Main Authors: Yuuta Moriyama, Fumihiro Ito, Hiroyuki Takeda, Tohru Yano, Masataka Okabe, Shigehiro Kuraku, Fred W. Keeley, Kazuko Koshiba-Takeuchi
Format: Article
Language:English
Published: Nature Portfolio 2016-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms10397