A mouse model of post-arthroplasty Staphylococcus aureus joint infection to evaluate in vivo the efficacy of antimicrobial implant coatings.

Post-arthroplasty infections represent a devastating complication of total joint replacement surgery, resulting in multiple reoperations, prolonged antibiotic use, extended disability and worse clinical outcomes. As the number of arthroplasties in the U.S. will exceed 3.8 million surgeries per year...

Full description

Bibliographic Details
Main Authors: Nicholas M Bernthal, Alexandra I Stavrakis, Fabrizio Billi, John S Cho, Thomas J Kremen, Scott I Simon, Ambrose L Cheung, Gerald A Finerman, Jay R Lieberman, John S Adams, Lloyd S Miller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2935351?pdf=render