New insights on hyperglycemia in 17-hydroxylase/17,20-lyase deficiency

New insights on hyperglycemia in 17-hydroxylase/17,20-lyase deficiency

ObjectiveThe adrenal glands of patients with 17-hydroxylase/17,20-lyase deficiency (17OHD) synthesize excessive 11-deoxycorticosterone(DOC) and progesterone, and produce less amount of sex steroid production. Mineralocorticoids and sex hormones play an important role in regulating glucose homeostasi...

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Bibliographic Details
Main Authors: Lingling Xu, Lin Lu, Anli Tong, Shi Chen, Wei Li, Huabing Zhang, Fan Ping, Yuxiu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Endocrinology
Subjects:
17-hydroxylase/17
20-lyase deficiency
diabetes
impaired glucose tolerance
high progesterone
hypokelamia
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.917420/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.917420/full

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