Muscle structure influences utrophin expression in mdx mice.
Duchenne muscular dystrophy (DMD) is a severe muscle wasting disorder caused by mutations in the dystrophin gene. To examine the influence of muscle structure on the pathogenesis of DMD we generated mdx4cv:desmin double knockout (dko) mice. The dko male mice died of apparent cardiorespiratory failur...
Päätekijät: | , , , , |
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Aineistotyyppi: | Artikkeli |
Kieli: | English |
Julkaistu: |
Public Library of Science (PLoS)
2014-06-01
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Sarja: | PLoS Genetics |
Linkit: | http://europepmc.org/articles/PMC4055409?pdf=render |