Muscle structure influences utrophin expression in mdx mice.

Muscle structure influences utrophin expression in mdx mice.

Duchenne muscular dystrophy (DMD) is a severe muscle wasting disorder caused by mutations in the dystrophin gene. To examine the influence of muscle structure on the pathogenesis of DMD we generated mdx4cv:desmin double knockout (dko) mice. The dko male mice died of apparent cardiorespiratory failur...

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Dades bibliogràfiques
Autors principals: Glen B Banks, Ariana C Combs, Guy L Odom, Robert J Bloch, Jeffrey S Chamberlain
Format: Article
Idioma:English
Publicat: Public Library of Science (PLoS) 2014-06-01
Col·lecció:PLoS Genetics
Accés en línia:http://europepmc.org/articles/PMC4055409?pdf=render

Internet

http://europepmc.org/articles/PMC4055409?pdf=render

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