Evaluation of Cytogenetic Changes and FLT3 mutations in Patients with Acute Promyelocytic Leukemia

Evaluation of Cytogenetic Changes and FLT3 mutations in Patients with Acute Promyelocytic Leukemia

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"nIntroduction: The secondary genetic changes other than the PML-RARA fusion gene may contribute to the acute promyelocytic leukemogenesis. Chromosomal alterations and mutation of FLT3 tyrosine kinase receptor are the frequent genetic alterations in acute myeloid leukemia (AML). However, th...

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Bibliographic Details
Main Authors: Marjan Yaghmaie, Hossein Mozdarani, Kamran Alimoghaddam, Ardeshir Ghavamzadeh, Seyed Hamiollah Ghaffari
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2010-07-01
Series:International Journal of Hematology-Oncology and Stem Cell Research
Subjects:
Acute promyelocytic leukemia
FLT3 tyrosine kinase
Internal tandem duplication
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/18608.pdf&manuscript_id=18608

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http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/18608.pdf&manuscript_id=18608

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