Generation of Hepatobiliary Cell Lineages from Human Induced Pluripotent Stem Cells: Applications in Disease Modeling and Drug Screening

Generation of Hepatobiliary Cell Lineages from Human Induced Pluripotent Stem Cells: Applications in Disease Modeling and Drug Screening

The possibility to reproduce key tissue functions in vitro from induced pluripotent stem cells (iPSCs) is offering an incredible opportunity to gain better insight into biological mechanisms underlying development and disease, and a tool for the rapid screening of drug candidates. This review attemp...

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Bibliographic Details
Main Authors: Mattia Pasqua, Roberto Di Gesù, Cinzia Maria Chinnici, Pier Giulio Conaldi, Maria Giovanna Francipane
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
iPSCs
hepatocytes
cholangiocytes
disease modeling
drug testing
tissue engineering
Online Access:https://www.mdpi.com/1422-0067/22/15/8227

Internet

https://www.mdpi.com/1422-0067/22/15/8227

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