The LYMPH trial: comparing microsurgical with conservative treatment for chronic breast cancer-associated lymphoedema – study protocol of a pragmatic randomised international multicentre superiority trial

The LYMPH trial: comparing microsurgical with conservative treatment for chronic breast cancer-associated lymphoedema – study protocol of a pragmatic randomised international multicentre superiority trial

Introduction Up to one-fifth of breast cancer survivors will develop chronic breast cancer-related lymphoedema (BCRL). To date, complex physical decongestion therapy (CDT) is the gold standard of treatment. However, it is mainly symptomatic and often ineffective in preventing BCRL progression. Lymph...

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Bibliographic Details
Main Authors: Andrea L Pusic, Matthias Schwenkglenks, Karin Ribi, Jane Shaw, Shan Shan Qiu, Walter Weber, Martin Halle, Khalil Zaman, Raymund E Horch, Marco Cattaneo, Cristina Granziera, Elisabeth A Kappos, Alexandra Schulz, Yves Harder, Rosine Mucklow, Martin Haug, Lars Hemkens, Daniel Staub, Marcus Vetter, Jaume Masia Ayala, Gemma Pons, Yvonne Haas, Florian Peters, Shakuntala Savanthrapadian, Julia Stoffel, Maria C Katapodi, Benedict Kaiser, Alexander Haumer, Stephanie Etter, Tristan M Handschin, Steffen Eisenhardt, Giuseppe Visconti, Gianluca Franceschini, Lorenzo Scardina, Benedetto Longo, Jan A Plock, Mario Scaglioni, Eduardo G Gonzalez, Sergio D Quildrian, Gunther Felmerer, Babak J Mehrara, Daniel F Kalbermatten, Justin M Sacks, Maximillian V Muntean, Erin M Taylor, Maria Mani, Florian J Jung, Pietro G di Summa, Efterpi Demiri, Dimitris Dionyssiou, Anne K Groth, Norbert Heine, Joshua Vorstenborsch, Kathryn V Isaac, Patricia E Engels, Axelle Serre, Anna-Lena Eberhardt, Sonja Ebner, Yvette Stoel, Cornelia Leo, Phillip Blondeel, Bjoern Behr, Ulrich Kneser, Lukas Prantl, Daniel T Boll, Nicole Lindenblatt, Dirk J Schaefer, Christoph Hirche, Katrin Seidenstuecker
Format: Article
Language:English
Published: BMJ Publishing Group 2025-02-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/2/e090662.full

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https://bmjopen.bmj.com/content/15/2/e090662.full

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