In Vivo Assembly of a <i>Dictyostelium</i> Lamin Mutant Induced by Light, Mechanical Stress, and pH

In Vivo Assembly of a <i>Dictyostelium</i> Lamin Mutant Induced by Light, Mechanical Stress, and pH

We expressed <i>Dictyostelium</i> lamin (NE81) lacking both a functional nuclear localization signal and a CAAX-box for C-terminal lipid modification. This lamin mutant assembled into supramolecular, three-dimensional clusters in the cytosol that disassembled at the onset of mitosis and...

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Bibliographic Details
Main Authors: Marianne Grafe, Phillip Hofmann, Petros Batsios, Irene Meyer, Ralph Gräf
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cells
Subjects:
lamin
NE81
<i>Dictyostelium</i>
nuclear envelope
nuclear lamina
Online Access:https://www.mdpi.com/2073-4409/9/8/1834

Internet

https://www.mdpi.com/2073-4409/9/8/1834

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