Design and immunological evaluation of two-component protein nanoparticle vaccines for East Coast fever

Design and immunological evaluation of two-component protein nanoparticle vaccines for East Coast fever

Nanoparticle vaccines usually prime stronger immune responses than soluble antigens. Within this class of subunit vaccines, the recent development of computationally designed self-assembling two-component protein nanoparticle scaffolds provides a powerful and versatile platform for displaying multip...

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Bibliographic Details
Main Authors: Anna Lacasta, Hyung Chan Kim, Elizabeth Kepl, Rachael Gachogo, Naomi Chege, Rose Ojuok, Charity Muriuki, Stephen Mwalimu, Gilad Touboul, Ariel Stiber, Elizabeth Jane Poole, Nicholas Ndiwa, Brooke Fiala, Neil P. King, Vishvanath Nene
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
protein nanoparticles
nanoparticle vaccines
livestock vaccines
tick-borne disease
East Coast fever
cattle
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1015840/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1015840/full

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