Effects of canagliflozin on cardiac remodeling and hemodynamic parameters in patients with type 2 diabetes mellitus

Abstract Sodium-glucose cotransporter type 2 (SGLT2) inhibitors have demonstrated to reduce cardiovascular risk in patients with type 2 diabetes mellitus (T2DM) in large trials independent of glycemic control. The mechanisms of this cardioprotective property remain uncertain. Evidence suggests posit...

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Autori principali: Hsiao-Huai Kuo, Yau-Huei Lai, Po-Lin Lin, Hsin-Hao Chen, Chung-Lieh Hung, Lawrence Yu-Min Liu, Chih-Kuang Yeh
Natura: Articolo
Lingua:English
Pubblicazione: Nature Portfolio 2023-12-01
Serie:Scientific Reports
Accesso online:https://doi.org/10.1038/s41598-023-48716-y