Placental imprinting of SLC22A3 in the IGF2R imprinted domain is conserved in therian mammals
Abstract Background The eutherian IGF2R imprinted domain is regulated by an antisense long non-coding RNA, Airn, which is expressed from a differentially methylated region (DMR) in mice. Airn silences two neighbouring genes, Solute carrier family 22 member 2 (Slc22a2) and Slc22a3, to establish the I...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2022-08-01
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| Series: | Epigenetics & Chromatin |
| Online Access: | https://doi.org/10.1186/s13072-022-00465-4 |